A Healthy Indonesian Traditional Food Against Methicillin Resistant Staphylococcus aureus Bacteria (MRSA)
Abstract
Penjang Pangi merupakan makanan tradisional yang terdiri atas bawang putih (Allium sativum), sereh (Cymbopogon citratus), pangi (Pangium edule). Pada penelitian ini, Penjang pangi di ekstrak dengan pelarut n-heksan, etanol dan methanol, masing masing pada konsentrasi 5%, 10%, dan 15%. Aktivitas antibakteri ekstrak Penjang Pangi di uji ke Bakteri Methicillin Resisten Staphylococcus aureus (MRSA) dengan menggunakan metode difusi agar kertas cakram. Hasil Penelitian menunjukkan bahwa Pelarut n-heksan dan etanol tidak memperlihatkan aktivitas antibakteri. Metanol 15% memperlihatkan aktivitas antibakteri dengan rata-rata zona hambat yang dibentuk 15 mm, 13.67 mm, dan 13 mm. Daya hambat yang dibentuk ekstrak Penjang Pangi tergolong sangat aktif, karena diatas >8 mm.
Kata kunci: Aktivitas antibakteri, Penjang Pangi, Bakteri Methicillin Resisten Staphylococcus aureus.
Keywords
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Adepu, S., & Khandelwal, M. (2017). Broad-spectrum antimicrobial activity of bacterial cellulose silver nanocomposites with sustained release. Journal of Materials Science 2017 53:3, 53(3), 1596–1609. https://doi.org/10.1007/S10853-017-1638-9
Akinyele, T. A., Igbinosa, E. O., Akinpelu, D. A., & Okoh, A. I. (2017). In vitro assessment of the synergism between extracts of Cocos nucifera husk and some standard antibiotics. Asian Pacific Journal of Tropical Biomedicine, 7(4), 306–313. https://doi.org/10.1016/J.APJTB.2016.12.022
Castelli, F., & Sulis, G. (2017). Migration and infectious diseases. In Clinical Microbiology and Infection (Vol. 23, Issue 5, pp. 283–289). Elsevier B.V. https://doi.org/10.1016/j.cmi.2017.03.012
Chakraborty, S., Afaq, N., Singh, N., & Majumdar, S. (2018). Antimicrobial activity of Cannabis sativa, Thuja orientalis and Psidium guajava leaf extracts against methicillin-resistant Staphylococcus aureus. Journal of Integrative Medicine, 16(5), 350–357. https://doi.org/10.1016/J.JOIM.2018.07.005
Cunha, S. C., & Fernandes, J. O. (2018). Extraction techniques with deep eutectic solvents. TrAC Trends in Analytical Chemistry, 105, 225–239. https://doi.org/10.1016/J.TRAC.2018.05.001
Dubey, N. K., Dwivedy, A. K., Chaudhari, A. K., & Das, S. (2018). Common Toxic Plants and Their Forensic Significance. Natural Products and Drug Discovery: An Integrated Approach, 349–374. https://doi.org/10.1016/B978-0-08-102081-4.00013-7
Elgayyar, M., Draughon, F. A., Golden, D. A., & Mount, J. R. (2001). Antimicrobial Activity of Essential Oils from Plants against Selected Pathogenic and Saprophytic Microorganisms. Journal of Food Protection, 64(7), 1019–1024. https://doi.org/10.4315/0362-028X-64.7.1019
Escorsim, A. M., da Rocha, G., Vargas, J. V. C., Mariano, A. B., Ramos, L. P., Corazza, M. L., & Cordeiro, C. S. (2018). Extraction of Acutodesmus obliquus lipids using a mixture of ethanol and hexane as solvent. Biomass and Bioenergy, 108, 470–478. https://doi.org/10.1016/J.BIOMBIOE.2017.10.035
Esonye, C., Onukwuli, O. D., Anadebe, V. C., Ezeugo, J. N. O., & Ogbodo, N. J. (2021). Application of soft-computing techniques for statistical modeling and optimization of Dyacrodes edulis seed oil extraction using polar and non-polar solvents. Heliyon, 7(3), e06342. https://doi.org/10.1016/J.HELIYON.2021.E06342
Furner-Pardoe, J., Anonye, B. O., Cain, R., Moat, J., Ortori, C. A., Lee, C., Barrett, D. A., Corre, C., & Harrison, F. (2020). Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients. Scientific Reports 2020 10:1, 10(1), 1–14. https://doi.org/10.1038/s41598-020-69273-8
Gao, W., & Zhang, L. (2020). Nanomaterials arising amid antibiotic resistance. Nature Reviews Microbiology 2020 19:1, 19(1), 5–6. https://doi.org/10.1038/s41579-020-00469-5
Gu, J., Xiao, P., Chen, J., Liu, F., Huang, Y., Li, G., Zhang, J., & Chen, T. (2014). Robust preparation of superhydrophobic polymer/carbon nanotube hybrid membranes for highly effective removal of oils and separation of water-in-oil emulsions. Journal of Materials Chemistry A, 2(37), 15268–15272. https://doi.org/10.1039/C4TA01603C
Hodille, E., Rose, W., Diep, B. A., Goutelle, S., Lina, G., & Dumitrescu, O. (2017). The role of antibiotics in modulating virulence in staphylococcus aureus. Clinical Microbiology Reviews, 30(4), 887–917. https://doi.org/10.1128/CMR.00120-16
Kaur, H., Bhardwaj, U., & Kaur, R. (2021). Cymbopogon nardus essential oil: a comprehensive review on its chemistry and bioactivity. Https://Doi.Org/10.1080/10412905.2021.1871976, 33(3), 205–220. https://doi.org/10.1080/10412905.2021.1871976
Kourmouli, A., Valenti, M., van Rijn, E., Beaumont, H. J. E., Kalantzi, O.-I., Schmidt-Ott, A., & Biskos, G. (2018). Can disc diffusion susceptibility tests assess the antimicrobial activity of engineered nanoparticles? Journal of Nanoparticle Research 2018 20:3, 20(3), 1–6. https://doi.org/10.1007/S11051-018-4152-3
Palanker, N. D., Lee, C.-T., Weltman, R. L., Tribble, G. D., van der Hoeven, R., Hong, J., & Wang, B. (2019). Antimicrobial Efficacy Assessment of Human Derived Composite Amnion-Chorion Membrane. Scientific Reports 2019 9:1, 9(1), 1–11. https://doi.org/10.1038/s41598-019-52150-4
Piekarska-Radzik, L., & Klewicka, E. (2020). Mutual influence of polyphenols and Lactobacillus spp. bacteria in food: a review. European Food Research and Technology 2020 247:1, 247(1), 9–24. https://doi.org/10.1007/S00217-020-03603-Y
Rowe, T. A., & Linder, J. A. (2019). Novel approaches to decrease inappropriate ambulatory antibiotic use. Https://Doi.Org/10.1080/14787210.2019.1635455, 17(7), 511–521. https://doi.org/10.1080/14787210.2019.1635455
Turner, N. A., Sharma-Kuinkel, B. K., Maskarinec, S. A., Eichenberger, E. M., Shah, P. P., Carugati, M., Holland, T. L., & Fowler, V. G. (2019). Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research. Nature Reviews Microbiology 2019 17:4, 17(4), 203–218. https://doi.org/10.1038/s41579-018-0147-4
DOI: http://dx.doi.org/10.21043/jobe.v4i2.12041
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